Cost, side effects, dosage, how to use, and more

Here are answers to some frequently asked questions about Tyrvaya.

Can I use an allergy nasal spray during Tyrvaya treatment?

Yes, however, be sure to talk with your doctor first. You should ask them for their advice regarding the timing of your doses. They may recommend spacing out the doses of your allergy nasal spray and Tyrvaya or using the medications in a specific order.

Keep in mind that Tyrvaya was not studied in people with severe seasonal allergies, rhinitis, or sinusitis. It’s possible that the drug may not work as well in people with nasal congestion due to these conditions. More research is needed to know for sure.

If you have additional questions about allergy nasal sprays and Tyrvaya, talk with your doctor.

Why can’t I spray Tyrvaya directly in my eyes for dry eye?

Tyrvaya is not meant to be used directly in the eyes. It’s believed the drug works by stimulating nerves in your nose. This helps your eyes produce tears and other moistening substances. (To learn more, see the “How Tyrvaya works” section above.)

Many other dry eye treatments come as eye drops, which can be difficult to use. It’s often tricky to feel whether you put the right number of drops into your eye. It’s also possible that you might miss your eye or blink at the wrong time.

In addition, many medicated eye drops commonly cause eye-related side effects, such as stinging or burning. These effects can be uncomfortable when your eyes are already irritated from dry eye disease.

Tyrvaya is the first dry eye medication that comes as a nasal spray. A key advantage of it is that the drug does not cause further discomfort to your eyes. It’s also easy to use.

If you’d like to learn more about Tyrvaya and other dry eye treatments, talk with your doctor or pharmacist.

If I sneeze after using Tyrvaya, should I take another dose?

No. People who participated in clinical trials of Tyrvaya for dry eye were told not to repeat their dose after sneezing. The drug was still shown to be an effective treatment for dry eye in these trials.

Sneezing is the most common side effect of Tyrvaya. If you have questions about this or any other side effects of the medication, ask your doctor or pharmacist.

Is Tyrvaya used to help people quit smoking?

No, Tyrvaya is used to treat the symptoms of dry eye disease. It’s not approved to help with quitting smoking.

Tyrvaya contains the active drug varenicline, which is also the active drug in Chantix. This is an oral tablet used to help people quit smoking. The manufacturer of Chantix recently recalled all Chantix tablets because they contained an impurity called a nitrosamine. High levels of nitrosamines may increase the risk of cancer. Tyrvaya nasal spray is not included in this recall, and the drug is not known to contain nitrosamines.

Because Tyrvaya is a nasal spray, very little of its active drug is absorbed into your bloodstream. This means that Tyrvaya is not likely to have any effect on whether or not you successfully quit smoking.

Your doctor and pharmacist should be able to provide you with helpful suggestions about how to quit smoking.